Brisbane Australiaįillard P, Pennec X, Arsigny V and Ayache N (2007) Clinical DT-MRI estimation, smoothing and fiber tracking with log-Euclidean metrics Asclepios Reseach Team, INRIA Sophia Antipolis of MICCAI ’07 workshop on interaction in medical image analysis and visualization. Toussaint N, Souplet JC, and Fillard P (2007) MedINRIA: medical image navigation and research tool by INRIA. Saksena S, Middleton DM, Krisa L, Shah P, Faro SH, Sinko R, Gaughan J, Finsterbusch J, Mulcahey MJ, Mohamed FB (2016) Diffusion tensor imaging of the normal cervical and thoracic pediatric spinal cord. Haakma W, Dik P, ten Haken B, Froeling M, Nievelstein RA, Cuppen I, de Jong TP, Leemans A (2014) Diffusion tensor magnetic resonance imaging and fiber tractographie of the sacral plexus in children with spina bifida. Zh Vopr Neirokhir Im N N Burdenko 80(3):66–73 A prognosis on the basis of spinal 3T MRI tractography. Sysoev KV, Tadevosyan AR, Nazinkina YV, Khachatryan VA (2016) (2016) Surgical treatment outcomes in children with tethered spinal cord syndrome. Tsuchiya K, Fujikawa A, Honya K, Nitatori T, Suzuki Y (2008) Diffusion tensor tractography of the lower spinal cord. Ann N Y Acad Sci 1064:50–60įilippi CG, Andrews T, Gonyea JV, Linnell G, Cauley KA (2010) Magnetic resonance diffusion tensor imaging and tractography of the lower spinal cord: application to diastematomyelia and tethered cord. Maier SE, Mamata H (2005) Diffusion tensor imaging of the spinal cord. NMR Biomed 15(7–8):468–480Ĭlark CA, Werring DJ (2002) Diffusion tensor imaging in spinal cord: methods and applications-a review. Mori S, van Zijl PC (2002) Fiber tracking: principles and strategies-a technical review. Wieshmann UC, Clark CA, Symms MR, Franconi F, Barker GJ, Shorvon SD (1999) Reduced anisotropy of water diffusion in structural cerebral abnormalities demonstrated with diffusion tensor imaging. Khalil C, Hancart C, Le Thuc V, Chantelot C, Chechin D, Cotton A (2008) Diffusion tensor imaging and tractographie of the median nerve in carpal tunnel syndrome: preliminary results. Tournier JD, Mori S, Leemans A (2011) Diffusion tensor imaging and beyond. J Magn Reson B 103:247–254ĭouek P, Turner R, Pekar J, Patronas N, Le Bihan D (1991) Mr color mapping of myelin fiber orientation. pp 445–474īasser PJ, Mattiello J, LeBihan D (1994) Estimation of the effective self-diffusion tensor from the NMR spin echo. In: Spina Bifida, Management and Outcome. Zerah M, Roujeau T, Catala M, Pierre-Kahn A (2008) Spinal Lipomas. Pierre-Kahn A, Zerah M, Renier D (1995) Lipomes malformatifs intrarachidiens. Operative Technique in Pediatric Neurosurgery 2(60):707–734 Mitchell JB, Pang D (2008) Surgical management of spinal dysraphism. It is during the probable myelination phase that the majority of symptoms appear. Analysis of the FA shows that the presence of a lipoma seems to have an effect on the myelination of the conus medullaris. Tractography of the conus medullaris in a very young pediatric population (0–8 years old) with a spinal lipoma is possible, reproductive, and allows visualization of the spinal cord within the dysraphism. Destruction or disorganization of fibers and any passing inside the lipomas was not observed. The conus medullaris was deformed and shifted. The tractography obtained in each case was coherent with morphologic sequences and reproducible. However, no significant differences in the mean values of FA, RD, and MD between the level of the lipoma and the level above were noted. We found a significant difference in the FA ( p = 0.024) between two age groups ( 24 months old). The diffusion parameters have been calculated by Osirix DTImap plugin. Tractography reconstruction of the conus medullaris of 12 patients were obtained using the MedINRIA software. Twelve patients (0–8 years) related to spinal lipomas treated between May 2017 and March 2018 were included. In a preliminary work, spinal lipoma was chosen for analyzing the micro-architecture parameters and fiber morphology of the spinal cord by DTI with tractography. One of the major challenges in dysraphism is to know the morphologic organization of the spinal cord. Diffusion tensor imaging (DTI) allows studying the micro and macro architecture.
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